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Table 5 Effect of testosterone replacement therapy on behavior in individuals with 49,XXXXY

From: DNA methylation and behavioral dysfunction in males with 47,XXY and 49,XXXXY: a pilot study

 

Received T

Did not receive T

P value

CBCL total problems

58.66 (40.0, 82.0)

67.10 (49.0, 78.0)

0.04

CBCL externalizing problems

54.3 (34.0, 75.0)

62.5 (48.0, 79.0)

0.04

CBCL internalizing problems

57.6 (34.0, 92.0)

62.9 (45.0, 75.0)

0.24

BRIEF BRI

57.2 (39.0, 88.0)

60.9 (50.0, 87.0)

0.54

BRIEF MI

56.7 (35.0, 75.0)

64.9 (50.0, 79.0)

0.11

BRIEF global

58.3 (36.0, 78.0)

64.7 (51.0, 85.0)

0.24