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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Integrative genomics analysis of nasal intestinal-type adenocarcinomas demonstrates the major role of CACNA1C and paves the way for a simple diagnostic tool in male woodworkers

Fig. 3

Analyses of Methylome data. (A) Epi-Manhattan plot reporting the epigenome-wide association study and the top first significant locus on CACNA1C/CACNA1C-AS1. (B) Zoomed view on the genomic context of the CACNA1C/CACNA1C-AS1 locus. (C) β values of the CpG probes on the CACNA1C/CACNA1C-AS1 locus in cancerous and non-cancerous nasal cavity samples. The horizontal line corresponding to a β value of 0.2 delimits the threshold between unmethylated status and hemimethylated status for each CpG probe. (D) Epi-Manhattan plot reporting the epigenome-wide association study and the top first significant locus on SLC26A10. (E) Zoomed view on the genomic context of the SLC26A10 locus. (F) β values of the CpG probes on the SLC26A10 locus in cancerous and non-cancerous nasal cavity samples. The horizontal line corresponding to a β value of 0.2 delimits the threshold between unmethylated status and hemimethylated status for each CpG probe

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Clinical Epigenetics

ISSN: 1868-7083

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