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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Methylation status of genes escaping from X-chromosome inactivation in patients with X-chromosome rearrangements

Fig. 1

Rearrangements of the X chromosome in the four patients. The black down arrow exhibits the rearrangements of the X chromosome in each patient. The upper chromosome in each patient shows a normal X chromosome. A box surrounded with dashed lines means a deleted region. A box surrounded with bold lines means a duplicated region. The region with an upside-down alphabet had inversion. The locations of escape genes are shown as asterisks. The locations of the three genes with abnormal methylation in Patient 1 are exhibited using colored asterisks (red: PNPLA4, blue: TCEANC, green: GPM6B). The loci which are important for the 3D structure of Xi are also shown with surrounding squares in Patient 1 and Patient 3. When important loci for the 3D structure are not included in duplication or deletion in each case, we did not show them in the figure. No patients had XIST on rearrangements

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