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Fig. 7 | Clinical Epigenetics

Fig. 7

From: Oxygen concentration affects de novo DNA methylation and transcription in in vitro cultured oocytes

Fig. 7

Identification of common CGIs between Kdm1s knock-out mouse M2 oocytes and in vitro cultured oocytes under treatments inhibiting methylation and transcription. a Venn diagrams showing the common and non-common CGIs between the hypermethylated domains defined in Kdm1a oocytes and the CGIs methylated > 25% in normoxia or 20% O2 CON and > 10% in MAO, LiCl, and MAO + LiCl. b Venn diagrams showing the common and non-common CGIs between the hypermethylated domains defined in Kdm1b oocytes and the CGIs methylated > 25% in normoxia or 20% O2 CON and > 10% in MAO, LiCl, and MAO + LiCl. c Heatmap representing the methylation level of 12 common CGIs between Kdm1a M2 oocytes and the CGIs methylated > 25% in normoxia or 20% O2 CON and > 10% in MAO, LiCl, and MAO + LiCl

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