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Table 1 Sample characteristics

From: Altered DNA methylation pattern reveals epigenetic regulation of Hox genes in thoracic aortic dissection and serves as a biomarker in disease diagnosis

 

Samples for WGBS*

TAD† (n = 6) Controls (n = 6)

Samples for replication

TAD (n = 6) Controls (n = 4)

Age, years

45.3 ± 11.6

42.8 ± 5.8‡

41.8 ± 8.0

36.5 ± 15.2§

Gender, male: female

5:1

6:0

5:1

3:1

Stanford classification

 Type A

6 (100%)

–

6 (100%)

–

 Type B

0

–

0

–

Dissection staging

 Acute phase

6 (100%)

–

6 (100%)

–

Chronic phase

0

–

0

–

Arteritis

0

0

0

0

Bicuspid aortic valve

0

0

0

0

Family history of aortic diseases

0

0

0

0

Rupture

0

–

0

–

Maximal aortic diameter (mm)

5.2 ± 1.5

–

5.7 ± 3.3

–

Emergent operation

6 (100%)

–

6 (100%)

–

Elective operation

0

–

0

–

  1. *WGBS whole genome bisulfite sequencing
  2. †TAD thoracic aortic dissection
  3. ‡P value = 0.646
  4. §P value = 0.497