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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Clinical and epigenetic features of colorectal cancer patients with somatic POLE proofreading mutations

Fig. 2

Detection of POLE proofreading mutations. Among 1,070 CRC tissues analysed, pathogenic somatic POLE proofreading mutations were detected in four CRCs (two cases were p.P286R [c.857C > G], one was p.V411L [c.1231G > C], and one was p.S459F [c.1376C > T]) and DNA from their corresponding normal mucosa displayed no germline mutations

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