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Fig. 7 | Clinical Epigenetics

Fig. 7

From: Increased PARylation impacts the DNA methylation process in type 2 diabetes mellitus

Fig. 7

Enrichment of 5hmC and 5fC within SOCS3 locus in low and high PAR T2DM patients and in control individuals. Percent of input detected in 5hmC, 5fC and IgG immunoprecipitated DNA fractions in mDIP experiments. Data are mean ± SD. Statistically significant differences as revealed by ANOVA and the Bonferroni post-hoc tests are indicated by the asterisks. *p ≤ 0.05, **p ≤ 0.01. N = 10 CT, 10 low PAR, 10 high PAR

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