From: Ultralow amounts of DNA from long-term archived serum samples produce high-quality methylomes
Group | Sample collection period | Sample source | Serum processing | Produced reads M range (mean) | Analysed Cs (M) range (mean) | Analysed for DNA yield (N) |
---|---|---|---|---|---|---|
1 | 1972–1978 | HE | Iodoacetate added | 287–889 (602) | 3642–12,188 (8102) | 10 |
2 | 1979–1986 | HE | No additives | 450–892 (707) | 6200–11,843 (9586) | 13 |
3 | 1987–2004 | HE | Separating gel tubes | 202–898 (644) | 2573–12,184 (8650) | 39 |
4 | 1973–1979 | RCBD | Lyophilisation | 376–889 (666) | 5005–12,270 (8983) | 14 |
5 | 1980–1990 | RCBD | No additives | 356–854 (626) | 4611–11,850 (8341) | 13 |
6 | 1997–2004 | RCBD | No additives | 327–685 (602) | 4881–9480 (8059) | 5 |
Total | 94 out of 96 | 94 out of 96 |