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Table 1 Samples groups from the Janus Serum Bank repository

From: Ultralow amounts of DNA from long-term archived serum samples produce high-quality methylomes

Group

Sample collection period

Sample source

Serum processing

Produced reads M range (mean)

Analysed Cs (M) range (mean)

Analysed for DNA yield (N)

1

1972–1978

HE

Iodoacetate added

287–889 (602)

3642–12,188 (8102)

10

2

1979–1986

HE

No additives

450–892 (707)

6200–11,843 (9586)

13

3

1987–2004

HE

Separating gel tubes

202–898 (644)

2573–12,184 (8650)

39

4

1973–1979

RCBD

Lyophilisation

376–889 (666)

5005–12,270 (8983)

14

5

1980–1990

RCBD

No additives

356–854 (626)

4611–11,850 (8341)

13

6

1997–2004

RCBD

No additives

327–685 (602)

4881–9480 (8059)

5

Total

   

94 out of 96

 

94 out of 96

  1. The samples are collected as part of national health examinations (HE), or from red cross donors (RCBD). Pre-analytical handling differs between groups. The last columns show the number of reads produced (millions, range and mean indicated), number of C analysed (millions, range and mean indicated) and number of samples used for calculating DNA yield, respectively. Further description of the groups can be found somewhere else [2, 4, 6]