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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Ultralow amounts of DNA from long-term archived serum samples produce high-quality methylomes

Fig. 2

Coverage and duplication information in the sequencing project for the 96 samples. a Distribution of the number of locations in the reference genome with a given depth of coverage. X axis is the coverage, and y-axis is the number of locations (millions). b Mean coverage box plot per sampling procedure. Median marked. c Fraction of the genome covered by at least X reads. X axis is the coverage, and Y axis is the fraction of the reference genome. d Complexity curves, total molecules vs unique molecules. The data up to x = 600 M are based on actual results, beyond that is a simulation/projection showing the expected diminishing returns of additional sequencing in terms of unique reads

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