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Table 5 Correlation of NEFM transcriptional expression/DNA methylation with MHC molecules based on TISIDB database

From: NEFM DNA methylation correlates with immune infiltration and survival in breast cancer

MHC molecules NEFM expression NEFM DNA methylation
TISIDB rho, n = 1100 p TISIDB rho, n = 785 p
B2M − 0.11 0.00025 − 0.287 2.85e−16
HLA-A − 0.093 0.00205 − 0.3 1.23e−17
HLA-B − 0.089 0.00388 − 0.315 1.58e−19
HLA-C − 0.077 0.0107 − 0.212 2.35e−09
HLA-DMA 0.058 0.0561 − 0.405  < 2.2e−16
HLA-DMB 0.03 0.313 − 0.414  < 2.2e−16
HLA-DOA 0.156 2.16e−07 − 0.458  < 2.2e−16
HLA-DOB 0.034 0.266 − 0.503  < 2.2e−16
HLA-DPA1 0.084 0.00511 − 0.407  < 2.2e−16
HLA-DPB1 0.153 3.46e−07 − 0.435  < 2.2e−16
HLA-DQA1 0.061 0.0446 − 0.398  < 2.2e−16
HLA-DQA2 0.057 0.058 − 0.294 5.78e−14
HLA-DQB1 0.081 0.00747 − 0.352  < 2.2e−16
HLA-DRA 0.061 0.0447 − 0.434  < 2.2e−16
HLA-DRB1 0.089 0.00329 − 0.39  < 2.2e−16
HLA-E 0.05 0.0991 − 0.484  < 2.2e−16
HLA-F  − 0.028 0.358 − 0.377  < 2.2e−16
HLA-G  − 0.04 0.189 − 0.231 6.32e−11
TAP1  − 0.204 8.63e−12 − 0.267 3.39e−14
TAP2  − 0.176 4.89e−09 − 0.381  < 2.2e−16
TAPBP − 0.143 1.91e−06 − 0.057 0.109
  1. Significant p value < 0.05 is in bold