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Table 2 Comparison of costs between different sequencing-based methods for DNA methylation analyses

From: High-resolution targeted bisulfite sequencing reveals blood cell type-specific DNA methylation patterns in IL13 and ORMDL3

  Bs-OS-Seq Hybridization-based
(e.g., SeqCap Epi)
Amplicon-based
(e.g., QIAseq)
Whole-genome bisulfite sequencing (WGBS)
Wet bench protocol Simple (resources: $) Complex
(resources: $$)
Complex
(resources: $$)
Simple
(resources: $)
Sequencing adapters Unmethylated
($)
Methylated
($$)
Unmethylated
($)
Methylated
($$)
Sequencing cost Targeted
($)
Targeted
($)
Targeted
($)
Whole-genome
($$$)