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Table 1 Participant characteristics

From: Weight loss after Roux-En-Y gastric bypass surgery reveals skeletal muscle DNA methylation changes

  Lean Pre-surgery obese Post-surgery obese P value
versus Lean Pre
P value
Pre versus Post
P value
Lean versus Post
Sex Four female Seven female    
Age (years) 38.5 ± 5.8 45.1 ± 3.6 45.3 ± 3.5 NS NS NS
Body mass index (kg/m2) 23.2 ± 0.9 42.1 ± 2.2 35.3 ± 1.8 < 0.001 < 0.001 < 0.01
Body fat (%) 30.3 ± 1.0 46.4 ± 1.2 40.6 ± 1.3 < 0.00001 < 0.01 < 0.001
Waist circumference (cm) 83.5 ± 3.2 122.7 ± 6.3 109.4 ± 109.4 < 0.01 < 0.0001 < 0.05
Systolic blood pressure (mmHg) 102.3 ± 12.6 125.1 ± 3.9 119.1 ± 4.6 NS NS NS
Diastolic blood pressure (mmHg) 59.8 ± 13.3 71.7 ± 2.0 75.1 ± 1.7 NS NS NS
Triglycerides (mg/dL) 92.8 ± 7.8 121.9 ± 17.5 107.7 ± 11.2 NS NS NS
Cholesterol (mg/dL) 202.3 ± 11.4 181.4 ± 13.2 151.5 ± 11.2 NS < 0.01 < 0.05
High-density lipoprotein (mg/dL) 63.0 ± 9.0 45.0 ± 2.7 45.0 ± 2.5 < 0.05 NS < 0.05
Low-density lipoprotein (mg/dL) 120.8 ± 7.6 112.1 ± 11.9 84.8 ± 10.5 NS < 0.01 < 0.05
Hemoglobin A1c % 5.3 ± 0.1 6.0 ± 0.2 5.7 ± 0.1 < 0.05 NS < 0.05
Fasting plasma glucose (mg/dL) 87.2 ± 3.1 104.2 ± 7.8 86.7 ± 3.1 NS < 0.05 NS
Fasting serum insulin (uIU/mL) 7.9 ± 4.2 18.2 ± 2.7 7.5 ± 1.0 < 0.01 < 0.01 NS
M-value (mg/kg/min) 6.7 ± 0.7 2.4 ± 0.3 2.9 ± 0.4 < 0.001 NS < 0.001
  1. Data are mean ± SEM