Skip to main content

Table 1 Clinical characteristics of the studied population with diffuse lower-grade gliomas (n = 166)

From: DNA methylation profiling for molecular classification of adult diffuse lower-grade gliomas

Variables Lower-grade gliomas (%)
Grade II, n = 74 Grade III, n = 92
Gender
 Female 26 (35) 40 (43)
 Ratio male:female 1.9 1.3
Age at diagnosis—years
 Mean ± SD 48 ± 13.5 41 ± 13.6
Age at diagnosis—groups
 18–29 7 (9) 16 (17)
 30–39 17 (23) 24 (26)
 40–49 17 (23) 23 (25)
 50–59 16 (22) 21 (23)
 60–69 15 (20) 6 (7)
 ≥ 70 2 (3) 2 (2)
Tumor location
 Frontal 40 (54) 51 (55)
 Insular 3 (4) 3 (3)
 Occipital 1 (1) 2 (2)
 Parietal 6 (8) 11 (12)
 Temporal 24 (32) 24 (26)
 Basal ganglia 0 1 (1)
Type of surgery
 Biopsy 6 (8) 2 (2)
 Resection 68 (92) 90 (98)
Size of tumor
 < 4 cm 17 (23) 14 (15)
 4–6 cm 31 (42) 49 (53)
 > 6 cm 26 (35) 29 (32)
Histopathological diagnosis (WHO 2007)
 Astrocytoma 45 (61) 46 (50)
 Oligoastrocytoma 15 (20) 30 (33)
 Oligodendroglioma 14 (19) 16 (17)
Molecular biomarkers
 IDH-mutant 14 (19) 1 (1)
 IDH-wildtype 2 (3) 4 (4)
 1p/19q codeletion 18 (24) 14 (15)
  1. SD, Standard deviation