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Table 1 Characteristics of available data sets: Mean (SD) or N (%) for every variable

From: Characteristics of epigenetic aging across gestational and perinatal tissues

 

ITU

PREDO

 

Cord blood

CVS

Placenta (fetal)

Cord blood (EPIC)

Cord blood (450 K)

Placenta (decidual)

Sample size

426

264

486

149

795

139

Gestational age (weeks)

40.04 (1.55)

12.79 (0.82)

39.99 (1.60)

39.87 (1.42)

39.74 (1.67)

39.89 (1.43)

Maternal alcohol use, yesc

40 (10)

24 (14)

48 (10)

16 (12)

115 (17)

17 (14)

Maternal smoking, yesa,b

18 (4)

29 (11)

20 (4)

13 (9)

32 (4)

13 (9)

Maternal mental disorders, yes

46 (11)

26 (9)

55 (11)

20 (14)

63 (8)

18 (13)

Maternal diabetes, yesa, c

93 (22)

57 (22)

105 (22)

26 (17)

222 (28)

20 (14)

Maternal hypertensive disorder, yesa, b, c

26 (6)

23 (9)

28 (6)

36 (24)

272 (34)

33 (24)

Maternal BMIa, b, c

23.94 (4.21)

24.20 (4.27)

23.82 (4.16)

25.23 (5.76)

27.38 (6.30)

24.85 (5.79)

Maternal age (years)a, b, c

34.70 (4.81)

34.96 (5.75)

34.59 (4.86)

32.13 (5.00)

33.33 (5.74)

32.04 (5.17)

Multiparous, yesb, c

193 (45)

153 (58)

235 (48)

85 (57)

558 (71)

74 (53)

Induced labor, yes

114 (27)

66 (25)

125 (26)

37 (25)

240 (30)

31 (22)

Delivery mode, aideda

129 (30)

87 (33)

145 (30)

51 (35)

233 (30)

55 (40)

Head circumference (cm)

35.10 (1.52)

35.04 (1.73)

35.07 (1.62)

35.21 (1.36)

35.13 (2.15)

35.19 (1.34)

Birth length (cm)a, b

50.23 (2.20)

50.13 (2.24)

50.17 (2.40)

49.77 (2.48)

50.21 (2.44)

49.65 (2.53)

Birth weight (g)a

3532 (489)

3489 (526)

3534 (509)

3454 (519)

3546 (559)

3425 (523)

Child sex, female

210 (49)

124 (47)

238 (49)

73 (49)

372 (47)

72 (52)

  1. Differences in predictor variables between the ITU and PREDO data sets were tested using t tests for continuous variables and Chi2 tests for categorical variables. Variables that showed nominal statistically significant differences (p < .05) are indicated as follows:
  2. aFor difference between ITU placenta vs. PREDO placenta data sets
  3. bFor difference between ITU cord blood vs. PREDO EPIC cord blood data sets
  4. cFor difference between ITU cord blood vs. PREDO 450 K cord blood data sets