From: Characteristics of epigenetic aging across gestational and perinatal tissues
 | ITU | PREDO | ||||
---|---|---|---|---|---|---|
 | Cord blood | CVS | Placenta (fetal) | Cord blood (EPIC) | Cord blood (450 K) | Placenta (decidual) |
Sample size | 426 | 264 | 486 | 149 | 795 | 139 |
Gestational age (weeks) | 40.04 (1.55) | 12.79 (0.82) | 39.99 (1.60) | 39.87 (1.42) | 39.74 (1.67) | 39.89 (1.43) |
Maternal alcohol use, yesc | 40 (10) | 24 (14) | 48 (10) | 16 (12) | 115 (17) | 17 (14) |
Maternal smoking, yesa,b | 18 (4) | 29 (11) | 20 (4) | 13 (9) | 32 (4) | 13 (9) |
Maternal mental disorders, yes | 46 (11) | 26 (9) | 55 (11) | 20 (14) | 63 (8) | 18 (13) |
Maternal diabetes, yesa, c | 93 (22) | 57 (22) | 105 (22) | 26 (17) | 222 (28) | 20 (14) |
Maternal hypertensive disorder, yesa, b, c | 26 (6) | 23 (9) | 28 (6) | 36 (24) | 272 (34) | 33 (24) |
Maternal BMIa, b, c | 23.94 (4.21) | 24.20 (4.27) | 23.82 (4.16) | 25.23 (5.76) | 27.38 (6.30) | 24.85 (5.79) |
Maternal age (years)a, b, c | 34.70 (4.81) | 34.96 (5.75) | 34.59 (4.86) | 32.13 (5.00) | 33.33 (5.74) | 32.04 (5.17) |
Multiparous, yesb, c | 193 (45) | 153 (58) | 235 (48) | 85 (57) | 558 (71) | 74 (53) |
Induced labor, yes | 114 (27) | 66 (25) | 125 (26) | 37 (25) | 240 (30) | 31 (22) |
Delivery mode, aideda | 129 (30) | 87 (33) | 145 (30) | 51 (35) | 233 (30) | 55 (40) |
Head circumference (cm) | 35.10 (1.52) | 35.04 (1.73) | 35.07 (1.62) | 35.21 (1.36) | 35.13 (2.15) | 35.19 (1.34) |
Birth length (cm)a, b | 50.23 (2.20) | 50.13 (2.24) | 50.17 (2.40) | 49.77 (2.48) | 50.21 (2.44) | 49.65 (2.53) |
Birth weight (g)a | 3532 (489) | 3489 (526) | 3534 (509) | 3454 (519) | 3546 (559) | 3425 (523) |
Child sex, female | 210 (49) | 124 (47) | 238 (49) | 73 (49) | 372 (47) | 72 (52) |