Table 1 Performance features of dual-marker detection model
Tests | Sensitivity (%) | Specificity (%) | Accuracy (%) | Prevalence (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|---|
Cohort 1 (model development) | ||||||
Dual marker | 87.1 | 82.9 | 85.4 | 60.4 | 88.6 | 80.8 |
Cohort 2 (validation) | ||||||
Dual marker | 88.1 | 89.7 | 88.8 | 60.2 | 92.9 | 83.3 |
Cohort 3 (validation 2-in general hematuria population) | ||||||
Dual marker | 91.2 | 85.7 | 86.8 | 19.5 | 60.8 | 97.6 |