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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Identification of ZBTB18 as a novel colorectal tumor suppressor gene through genome-wide promoter hypermethylation analysis

Fig. 1

CpG methylation in colorectal cancer cell lines. a The average (± SEM) methylation (beta-value) of all the 27,578 CpGs interrogated is shown in a panel of 45 colorectal cancer cell lines. Control − : whole genome amplification with GenomiPhi, GE Healthcare; Control + : in vitro methylated with SssI. Inset shows the correlation between methylation measurements for all CpGs in two replicates of SW48. b Histogram showing the percentage of the CpG dinucleotides interrogated that have average methylation levels across the 45 cell lines in the indicated intervals

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