HDAC2 enhances esophageal squamous cell carcinoma development through down-regulating microRNA-503-5p and promoting CXCL10

Table 2 Relationship between HDAC2 expression and clinicopathological traits of ESCC patients

Clinicopathological data	n	HDAC2 expression		P	x²
Clinicopathological data	n	Low expression group (n = 60)	High expression group (n = 61)	P	x²
Age (years)
≥ 59	49	26	23	0.528	0.4
< 59	72	34	38
Gender
Male	84	39	45	0.295	1.096
Female	37	21	16
Tumor diameter
< 5 cm	92	50	42	0.062	3.481
≥ 5 cm	29	10	19
Lymph node metastasis
Yes	45	18	27	0.105	2.634
No	76	42	34
Tumor node metastasis stage
I–II	63	38	25	0.014	6.054
III	58	22	36
Differentiation degree
Well or moderate	98	45	53	0.096	2.775
Poor	23	15	8

The data in this table are enumeration data, using Chi-square test. HDAC2, histone deacetylase-2; ESCC, esophageal squamous cell carcinoma

ISSN: 1868-7083