Table 1 Population characteristics according to the presence of undiagnosed chronic obstructive pulmonary disease (COPD)
General characteristics, mean ± SD | COPD− (n = 85) | COPD+ (n = 30) | p value |
|---|---|---|---|
Age, years | 63 ± 9 | 70 ± 8 | 0.001 |
BMI, Kg/m2 | 27.7 ± 4.2 | 27 ± 3.6 | 0.420 |
Male, n° (%) | 73 (86) | 23 (77) | 0.243 |
CV risk factors and comorbidities, n° (%) | |||
Diabetes | 19 (22) | 9 (30) | 0.401 |
Hypertension | 58 (68) | 18 (60) | 0.413 |
Family history of CAD | 23 (27) | 8 (27) | 0.967 |
Dyslipidemia | 47 (55) | 13 (43) | 0.260 |
Pre-MI | 10 (12) | 8 (27) | 0.053 |
Pre-PCI | 17 (20) | 3 (10) | 0.214 |
Pre-CABG | 3 (4) | 2 (7) | 0.469 |
AF | 8 (9) | 3 (10) | 0.925 |
PAD | 4 (5) | 2 (7) | 0.678 |
COPD parameters | Â | Â | Â |
RHSQ > 19, n° (%) | 25 (29) | 17 (57) | 0.008 |
FEV1, L, mean ± SD | 2.9 ± 0.7 | 2.0 ± 0.5 |  < 0.001 |
Smoker, n° (%) | 39 (46) | 15 (50) | 0.698 |
Former smokers, n° (%) | 46 (54) | 15 (50) | 0.698 |
Pack years, mean ± SD | 34 ± 23 | 45 ± 38 | 0.049 |
Clinical presentation and coronary vessel disease, n° (%) | |||
STEMI | 38 (45) | 15 (50) | 0.617 |
NSTEMI | 27 (32) | 10 (33) | 0.874 |
Unstable angina | 20 (24) | 5 (17) | 0.433 |
Descending artery | 67 (79) | 18 (60) | 0.051 |
Circumflex artery | 44 (52) | 12 (40) | 0.268 |
Right coronary artery | 61 (72) | 18 (60) | 0.232 |
Left main | 12 (14) | 5 (17) | 0.551 |
Therapy, n° (%) |  |  |  |
Aspirin | 84 (99) | 30(100) | 0.553 |
P2Y12 inhibitor | 85 (100) | 30(100) | 0.999 |
Beta-blockers | 72 (85) | 28(93) | 0.228 |
ACE inhibitors | 77 (91) | 28(93) | 0.646 |
Statins | 83 (98) | 28(93) | 0.268 |
Laboratory data, mean ± SD |  |  |  |
Troponin T, ng/dl | 1.99 ± 2.7 | 2.3 ± 4.3 | 0.643 |
CK-MB peak | 78 ± 119 | 90 ± 141 | 0.676 |
WBC admission, u/μl | 9.4 ± 3.05 | 9.5 ± 2.94 | 0.998 |
WBC discharge, u/μl | 8.48 ± 2.21 | 7.91 ± 1.88 | 0.209 |
Lymphocytes, u/μl, admission | 2.14 ± 0.99 | 1.95 ± 0.96 | 0.365 |
Lymphocytes, u/μl, discharge | 1.85 ± 0.57 | 1.74 ± 0.73 | 0.352 |
Neutrophils, u/μl, admission | 6.11 ± 2.66 | 5.95 ± 2.06 | 0.763 |
Neutrophils, u/μl, discharge | 5.56 ± 1.84 | 4.91 ± 1.36 | 0.081 |
NLR, admission | 3.47 ± 2.17 | 3.78 ± 2.51 | 0.516 |
NLR, discharge | 3.24 ± 1.44 | 3.39 ± 1.88 | 0.639 |