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Fig. 2 | Clinical Epigenetics

Fig. 2

From: The dark side of histones: genomic organization and role of oncohistones in cancer

Fig. 2

Localization of cancer-associated histone mutations. The most relevant somatic missense histone mutations for each core histone family are shown (red circles). Mutations were considered relevant depending on their recurrence in cross-cancer mutation summaries using cBioPortal and/or on the basis of the existence of studies that investigated their functional role. Globular domains are indicated by blue bars; sites of known PTMs are indicated by green circles. N-tt, N-terminal tail; C-tt, C-terminal tail

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