Fig. 4

Prediction of gestational age using the EPIC GA, 450 K/EPIC, and ETD-based clocks. Scatter plots of predicted gestational age using (a) the EPIC GA clock, (b) the 450 K/EPIC overlap clock, and (c) the ETD-based clock against gestational age estimated by ultrasound in a test set (n = 200) of non-ART newborns from START. The red line indicates a perfect correlation between DNAm-based gestational age and ultrasound-based gestational age. The black line indicates the MM-type robust regression of ultrasound-based gestational age on DNAm-based gestational age