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Table 2 Overview of the number of differentially methylated CpG sites in different group comparisons

From: DNA methylation in cord blood in association with prenatal depressive symptoms

   Whole Girls Boys
Group 1 Group 2 n1 n2 pa pu n1 n2 pa pu n1 n2 pa pu
Healthy control Prenatal depressive symptoms 194 165 0 49,385 98 77 0 43,762 96 88 0 35,603
History and prenatal depressive symptoms Prenatal depressive symptoms only 147 32 0 37,873 65 18 0 43,919 82 14 38 39,150
History and prenatal depressive symptoms Healthy control 147 194 0 44,372 65 98 0 37,458 82 96 0 35,522
Prenatal depressive symptoms only Healthy control 32 194 0 45,043 18 98 0 47,277 14 96 6 39,941
Anxiety and prenatal depressive symptoms Prenatal depressive symptoms only 95 70 0 56,366 41 36 0 46,103 54 34 0 44,805
Anxiety and prenatal depressive symptoms Healthy control 95 194 2 44,230 41 98 0 39,519 54 96 0 36,549
Prenatal depressive symptoms only Healthy control 70 194 0 62,013 36 98 0 50,096 34 96 0 41,260
Healthy control Prenatal depressive symptoms without SSRI 194 149 0 48,338 98 71 0 41,955 96 78 0 34,973
Healthy control Prenatal depressive symptoms with SSRI 194 13 14 44,881 98 4 109 48,451 96 9 14 49,785
Prenatal depressive symptoms without SSRI Prenatal depressive symptoms with SSRI 149 13 14 41,708 71 4 131 40,940 78 9 12 50,239
  1. pa = number of CpGs significant with p-value adjusted for multiple testing and for sample plate batch, sentrix position on the chip, granulocyte cell estimate, nucleated red blood cell estimate,  CD8T-cell estimate, maternal age at partus, pre-pregnancy body mass index, maternal place of birth, parity, gestational age, delivery mode, and maternal education
  2. pu = number of differentially methylated CpGs with an unadjusted significant p-value