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Table 3 Top 44 CpGs from EWAS study with Benjamini and Hochberg false discovery rate (FDR)‐adjusted p‐values < 0.05. The effect is estimate as the difference in % of methylation per 100 g in birthweight difference. In bold the CpG with the strongest effect

From: Birthweight DNA methylation signatures in infant saliva

CpG Chromosome Gene allocation or nearest gene Effect estimate Standard error Nominal p-value FDR corrected p-value
cg03045325 11 MACROD1 − 0.266 4.89E−06 3.53E−07 0.046
cg19854704 10 95 kb down ENSG00000286295 0.165 3.03E−06 3.56E−07 0.046
cg07728793 2 RAMP1 − 0.155 2.90E−06 4.91E−07 0.046
cg18072629 10 GATA3 − 0.112 2.13E−06 7.03E−07 0.046
cg05005073 1 10 kb up NDUFS5 0.233 4.44E−06 8.01E−07 0.046
cg09516627 2 CENPO 0.155 2.97E−06 8.07E−07 0.046
cg02727104 13 13 kb down SOHLH2 0.569 1.09E−05 8.7E−07 0.046
cg26725813 15 ZNF770 − 0.136 2.63E−06 9.99E−07 0.046
cg05931551 1 TUT4 − 0.290 5.61E−06 1.08E−06 0.046
cg26392737 8 DMTN 0.268 5.21E−06 1.21E−06 0.046
cg04512603 7 ZNF273 − 0.072 1.39E−06 1.24E−06 0.046
cg23218354 1 50 kb down ACTRT2 0.565 1.10E−05 1.4E−06 0.046
cg09855212 11 SYTL2 0.169 3.32E−06 1.43E−06 0.046
cg04305601 16 ZNF423 − 0.215 4.25E−06 1.72E−06 0.046
cg13590166 10 70 kb down WAC − 0.211 4.18E−06 1.86E−06 0.046
cg01807862 5 MCIDAS − 0.159 3.16E−06 1.91E−06 0.046
cg14781041 1 SIPA1L2 0.105 2.10E−06 2.25E−06 0.046
cg15915658 11 30 kb down SCYL1 0.307 6.14E−06 2.3E−06 0.046
cg03466415 2 SCN9A 0.142 2.85E−06 2.32E−06 0.046
cg22453818 5 LHFPL2 0.254 5.09E−06 2.43E−06 0.046
cg07175848 16 SNTB2 − 0.204 4.11E−06 2.7E−06 0.046
cg18971416 10 THNSL1 0.129 2.60E−06 2.72E−06 0.046
cg18152712 6 E2F3 0.115 2.32 E−06 2.76E−06 0.046
cg08060902 19 ZNF709 − 0.151 3.05 E−06 2.8E−06 0.046
cg04963607 7 PRKAR1B − 0.135 2.72 E−06 2.87E−06 0.046
cg00483825 10 CFAP46 − 0.157 3.19 E−06 2.99E−06 0.046
cg18417562 5 CTNNA1 − 0.198 4.03 E−06 3.07E−06 0.046
cg09361653 17 RPTOR − 0.192 3.91 E−06 3.18E−06 0.046
cg22896429 6 MTHFD1L 0.165 3.37 E−06 3.33E−06 0.046
cg19794939 11 LGR4 0.101 2.07 E−06 3.48E−06 0.046
cg03113121 19 FOXA3 0.178 3.63 E−06 3.49E−06 0.046
cg23114964 1 HIVEP3 − 0.229 4.69 E−06 3.67E−06 0.046
cg06527318 1 MIR4425 − 0.313 6.42 E−06 3.77E−06 0.046
cg20100049 11 KMT5B − 0.204 4.18 E−06 3.84E−06 0.046
cg20515787 11 SART1 0.108 2.21 E−06 3.91E−06 0.046
cg13680864 10 STAM 0.235 4.82 E−06 3.96E−06 0.046
cg23096644 7 SGCE 0.167 3.44 E−06 4.37E−06 0.047
cg03722643 2 GPR45 − 0.044 9.07 E−07 4.43E−06 0.047
cg19857227 14 ENSG00000240914 − 0.215 4.45 E−06 4.49E−06 0.047
cg08707988 6 41 kb up LOC100294145 − 0.258 5.33 E−06 4.51E−06 0.047
cg09749788 8 MCPH1-AS1 0.229 4.76 E−06 4.7E−06 0.047
cg06655187 17 ZNHIT3 0.125 2.59 E−06 4.79E−06 0.047
cg10800369 12 LMO3 0.327 6.80 E−06 4.91E−06 0.047
cg24864887 15 800b down ISL2 0.347 7.20 E−06 4.92E−06 0.047