Table 3 Top 44 CpGs from EWAS study with Benjamini and Hochberg false discovery rate (FDR)‐adjusted p‐values < 0.05. The effect is estimate as the difference in % of methylation per 100 g in birthweight difference. In bold the CpG with the strongest effect
From: Birthweight DNA methylation signatures in infant saliva
CpG | Chromosome | Gene allocation or nearest gene | Effect estimate | Standard error | Nominal p-value | FDR corrected p-value |
|---|---|---|---|---|---|---|
cg03045325 | 11 | MACROD1 | − 0.266 | 4.89E−06 | 3.53E−07 | 0.046 |
cg19854704 | 10 | 95 kb down ENSG00000286295 | 0.165 | 3.03E−06 | 3.56E−07 | 0.046 |
cg07728793 | 2 | RAMP1 | − 0.155 | 2.90E−06 | 4.91E−07 | 0.046 |
cg18072629 | 10 | GATA3 | − 0.112 | 2.13E−06 | 7.03E−07 | 0.046 |
cg05005073 | 1 | 10 kb up NDUFS5 | 0.233 | 4.44E−06 | 8.01E−07 | 0.046 |
cg09516627 | 2 | CENPO | 0.155 | 2.97E−06 | 8.07E−07 | 0.046 |
cg02727104 | 13 | 13 kb down SOHLH2 | 0.569 | 1.09E−05 | 8.7E−07 | 0.046 |
cg26725813 | 15 | ZNF770 | − 0.136 | 2.63E−06 | 9.99E−07 | 0.046 |
cg05931551 | 1 | TUT4 | − 0.290 | 5.61E−06 | 1.08E−06 | 0.046 |
cg26392737 | 8 | DMTN | 0.268 | 5.21E−06 | 1.21E−06 | 0.046 |
cg04512603 | 7 | ZNF273 | − 0.072 | 1.39E−06 | 1.24E−06 | 0.046 |
cg23218354 | 1 | 50 kb down ACTRT2 | 0.565 | 1.10E−05 | 1.4E−06 | 0.046 |
cg09855212 | 11 | SYTL2 | 0.169 | 3.32E−06 | 1.43E−06 | 0.046 |
cg04305601 | 16 | ZNF423 | − 0.215 | 4.25E−06 | 1.72E−06 | 0.046 |
cg13590166 | 10 | 70 kb down WAC | − 0.211 | 4.18E−06 | 1.86E−06 | 0.046 |
cg01807862 | 5 | MCIDAS | − 0.159 | 3.16E−06 | 1.91E−06 | 0.046 |
cg14781041 | 1 | SIPA1L2 | 0.105 | 2.10E−06 | 2.25E−06 | 0.046 |
cg15915658 | 11 | 30 kb down SCYL1 | 0.307 | 6.14E−06 | 2.3E−06 | 0.046 |
cg03466415 | 2 | SCN9A | 0.142 | 2.85E−06 | 2.32E−06 | 0.046 |
cg22453818 | 5 | LHFPL2 | 0.254 | 5.09E−06 | 2.43E−06 | 0.046 |
cg07175848 | 16 | SNTB2 | − 0.204 | 4.11E−06 | 2.7E−06 | 0.046 |
cg18971416 | 10 | THNSL1 | 0.129 | 2.60E−06 | 2.72E−06 | 0.046 |
cg18152712 | 6 | E2F3 | 0.115 | 2.32 E−06 | 2.76E−06 | 0.046 |
cg08060902 | 19 | ZNF709 | − 0.151 | 3.05 E−06 | 2.8E−06 | 0.046 |
cg04963607 | 7 | PRKAR1B | − 0.135 | 2.72 E−06 | 2.87E−06 | 0.046 |
cg00483825 | 10 | CFAP46 | − 0.157 | 3.19 E−06 | 2.99E−06 | 0.046 |
cg18417562 | 5 | CTNNA1 | − 0.198 | 4.03 E−06 | 3.07E−06 | 0.046 |
cg09361653 | 17 | RPTOR | − 0.192 | 3.91 E−06 | 3.18E−06 | 0.046 |
cg22896429 | 6 | MTHFD1L | 0.165 | 3.37 E−06 | 3.33E−06 | 0.046 |
cg19794939 | 11 | LGR4 | 0.101 | 2.07 E−06 | 3.48E−06 | 0.046 |
cg03113121 | 19 | FOXA3 | 0.178 | 3.63 E−06 | 3.49E−06 | 0.046 |
cg23114964 | 1 | HIVEP3 | − 0.229 | 4.69 E−06 | 3.67E−06 | 0.046 |
cg06527318 | 1 | MIR4425 | − 0.313 | 6.42 E−06 | 3.77E−06 | 0.046 |
cg20100049 | 11 | KMT5B | − 0.204 | 4.18 E−06 | 3.84E−06 | 0.046 |
cg20515787 | 11 | SART1 | 0.108 | 2.21 E−06 | 3.91E−06 | 0.046 |
cg13680864 | 10 | STAM | 0.235 | 4.82 E−06 | 3.96E−06 | 0.046 |
cg23096644 | 7 | SGCE | 0.167 | 3.44 E−06 | 4.37E−06 | 0.047 |
cg03722643 | 2 | GPR45 | − 0.044 | 9.07 E−07 | 4.43E−06 | 0.047 |
cg19857227 | 14 | ENSG00000240914 | − 0.215 | 4.45 E−06 | 4.49E−06 | 0.047 |
cg08707988 | 6 | 41 kb up LOC100294145 | − 0.258 | 5.33 E−06 | 4.51E−06 | 0.047 |
cg09749788 | 8 | MCPH1-AS1 | 0.229 | 4.76 E−06 | 4.7E−06 | 0.047 |
cg06655187 | 17 | ZNHIT3 | 0.125 | 2.59 E−06 | 4.79E−06 | 0.047 |
cg10800369 | 12 | LMO3 | 0.327 | 6.80 E−06 | 4.91E−06 | 0.047 |
cg24864887 | 15 | 800b down ISL2 | 0.347 | 7.20 E−06 | 4.92E−06 | 0.047 |