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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Integrative study of EZH2 mutational status, copy number, protein expression and H3K27 trimethylation in AML/MDS patients

Fig. 5

Decreased EZH2 protein expression is associated with inferior OS in AML patients. a OS of AML patients by EZH2 protein expression level. 21 patients in the EZH2-high and one patient in the EZH2-low group were censored (still alive at last follow-up). b OS of AML patients by EZH2 protein expression excluding EZH2-mutated patients. 20 patients in the EZH2-high and one patient in the EZH2-low group were censored (still alive at last follow-up). c Low EZH2 protein expression is associated with inferior OS in the subgroup of AML patients having received intensive therapy. 21 patients in the EZH2 high and one patient in the EZH2 low group were censored (still alive at last follow-up). d In AML patients having received non-intensive therapy, OS is similar in patients with high or low EZH2 expression

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Clinical Epigenetics

ISSN: 1868-7083

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