Table 1 Study descriptives
From: DNA methylation biomarker for cumulative lead exposure is associated with Parkinson’s disease
Demographic variable | SGPD | PEG | ||
|---|---|---|---|---|
PD (n = 959) | Control (n = 930) | PD (n = 569) | Control (n = 238) | |
Continuous variables: mean (SD) | ||||
Age* | 66.5 (9.1) | 64.9 (10.4) | 70.5 (9.8) | 67.5 (12.8) |
European fractional ancestry | NA | 0.87 (0.27) | 0.92 (0.18) | |
meanMethBySample | 0.26 (0.01) | 0.27 (0.01) | 0.29 (0.01) | 0.29 (0.01) |
DNAm tibia-lead | 2.57 (0.41) | 2.46 (0.49) | 2.65 (0.54) | 2.52 (0.52) |
DNAm patella-lead | 3.41 (0.4) | 3.48 (0.4) | 3.06 (0.4) | 3.03 (0.3) |
Categorical variables: n (%) | ||||
Male | 611 (63.7) | 428 (46.0) | 356 (62.6) | 127 (53.4) |
Former smoker | NA | 240 (42.4) | 125 (52.5) | |
Current smoker | 25 (4.2) | 17 (7.1) | ||