From: A review of epigenetic changes in asthma: methylation and acetylation
Author and year | Subjects | Specimen | Genes/regions | Phenotype | References |
---|---|---|---|---|---|
Kwon et al. 2008 | Adults | Venous blood, cultured CD4 +  | IL-4 and IFN-γ | Bronchial asthma | [33] |
Breton et al. 2011 | Children | Buccal cells | NOS1, NOS2A, NOS3, ARG1, and ARG2 | Childhood asthma | [23] |
Brand et al. 2012 | Female BALB/c mice and BALB/\({c}^{\mathrm{scid}}\) mice | Blood | CNS1 and IFN-γ | Asthma | [32] |
Baccarelli et al. 2012 | Children | Nasal cell | IL-6 and iNOS | Childhood asthma | [24] |
Verma et al. 2013 | Balb/c mice | lung, trachea tissues and BALF cells and Whole blood | DNMT1, Socs3, STAT3, IFN-y, IL-4, IL-5 and IL-6 | Asthma | [34] |
Gagné-Ouellet et al. 2015 | Adult and Children | Whole blood | IL1R1 and IL1R2 | Asthma and atopy | [41] |
Larouche et al. 2018 | Adults | Bronchial epithelial cell line | CCL26 and IL-33 | Asthma | [42] |
Forno et al. 2019 | Children | Nasal cells | 30 CpG regions | Atopy and atopic asthma | [36] |