Skip to main content
Fig. 5 | Clinical Epigenetics

Fig. 5

From: Epigenome-wide association study of whole blood gene expression in Framingham Heart Study participants provides molecular insight into the potential role of CHRNA5 in cigarette smoking-related lung diseases

Fig. 5

Genetic effects on smoking-related CpG sites and gene expression and the risk of COPD. Relations between genetic variant (rs17486278), DNA methylation (cg22563815) and gene expression (CHRNA5). Cg225638115 was found to be differentially methylated between current smokers and never smokers. This CpG is associated with the expression of CHRNA5. The CpG and CHRNA5 both are under genetic control of rs17486278, which has been found to be associated with COPD in previous GWAS

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us