|
Female
|
781 (71.0%)
|
|
Age (years)
|
57.1 (10.6)
|
|
Education (years)
|
12.3 (3.5)
|
|
Smoking status
|
|
Never
|
666 (60.5%)
|
|
Former
|
255 (23.2%)
|
|
Current
|
179 (16.3%)
|
|
Alcohol consumption (drinks/week)
|
0.66 (2.6)
|
|
BMI (kg/m2)
|
31.20 (6.6)
|
|
Type 2 diabetes
|
216 (19.6%)
|
|
Anti-hypertensive medication use
|
649 (59.0%)
|
|
Hypertension
|
771 (70.1%)
|
|
Epigenetic age acceleration
|
|
IEAA (years) (N = 1099)
|
0.15 (4.8)
|
|
EEAA (years)
|
0.27 (5.9)
|
|
PhenoAA (years) (N = 1099)
|
0.38 (7.2)
|
|
GrimAA (years) (N = 1099)
|
0.11 (5.0)
|
|
Cardiometabolic parameters
|
|
Systolic blood pressure (mmHg)
|
133.8 (21.6)
|
|
Diastolic blood pressure (mmHg)
|
77.7 (11.9)
|
|
Mean arterial pulse pressure (mmHg)
|
96.4 (13.5)
|
|
Pulse pressure (mmHg)
|
56.2 (17.7)
|
|
Glucose (mg/dl) (N = 883)
|
109.2 (42.1)
|
|
Insulin (mIU/l) (N = 882)
|
11.5 (13.4)
|
|
Total cholesterol (mg/dl) (N = 1098)
|
204.3 (45.2)
|
|
HDL-C (mg/dl)
|
55.2 (17.9)
|
|
LDL-C (mg/dl) (N = 1076)
|
120.8 (41.5)
|
|
Triglycerides (mg/dl) (N = 1099)
|
146.0 (82.1)
|
|
CVD 10-year risk scores
|
|
Framingham risk score (%) (N = 945)
|
14.4 (12.7)
|
|
ASCVD risk equation (%) (N = 988)
|
11.6 (11.1)
|
|
Prevalent CVD at baseline
|
91 (8.3%)
|
|
Incident CVD at follow-up
|
72 (8.8 per 1000 person-years)
|
