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Table 1 Baseline characteristics of participants in four European cohorts included in the meta-analysis of EWAS of prevalent T2D

From: DNA methylation of blood cells is associated with prevalent type 2 diabetes in a meta-analysis of four European cohorts

Cohort

N

N T2D cases (%)

Mean age in years (SD)

N males (%)

Mean FG in mmol/L (SD)

Mean BMI in kg/m2 (SD)

N current smokers (%)

ALSPAC

1050

48 (4.6)

49.9 (5.4)

405 (38.6)

5.4 (1.1)

26.8 (4.7)

97 (9.2)

LBC1936

915

110 (12.0)

69.6 (0.8)

462 (50.5)

NAa

27.8 (4.4)

103 (11.3)

RSIII-1

728

74 (10.2)

59.7 (8.1)

335 (46.0)

5.5 (1.1)

27.5 (4.7)

196 (26.9)

RS-Bios

735

108 (14.7)

67.6 (6.0)

312 (42.4)

5.7 (1.1)

27.7 (4.1)

77 (10.5)

Total

3428

340

61.7

1514

5.5

27.5

473

  1. Continuous variables were described using the mean and SD, and the frequency and percent for categorical variables
  2. SD, standard deviation; BMI, body mass index
  3. aMean values of fasting glucose (FG) were not available in LBC1936. Instead, mean levels of the hemoglobin A1c or HbA1c (%) was reported for these participants: 5.92% (SD = 0.71)