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Fig. 1 | Clinical Epigenetics

Fig. 1

From: DNA methylation of blood cells is associated with prevalent type 2 diabetes in a meta-analysis of four European cohorts

Fig. 1

Manhattan (a) and volcano plot (b) illustrating the association of DNAm in peripheral blood of middle-age and older adults, with prevalent T2D from a meta-analysis with four cohorts: ALSPAC, LBC1936, RSIII-1 and RS-Bios (n = 3,428 total; N = 340 T2D cases). Results were adjusted for age, sex, SVs, cell counts and smoking. Associations at p < 1.33 × 10–7 are above the horizontal red line in the Manhattan plot. The horizontal blue line indicates p < 1.0 × 10–5. The volcano plot shows the distribution of effect sizes against the − log10(p value) for all CpG sites. Associations at p < 1.33 × 10–7 are shown in red and those with p < 1.0 × 10–5 are highlighted in blue

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Clinical Epigenetics

ISSN: 1868-7083

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