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Table 2 GMDs with the highest numbers of strong trans-correlations between their expression and methylation levels of target individual probes and gene regions in pancancer analysis

From: Association of expression of epigenetic molecular factors with DNA methylation and sensitivity to chemotherapeutic agents in cancer cell lines

GMD Positive correlations Negative correlations
GMDs correlated with ≥ 5 individual probes
SETDB1 422 1
CBX2 383 0
KDM2B 352 1
TET3 280 0
DNMT3A 43 0
MGMT 39 0
TDG 20 0
DNMT1 11 0
EHMT2 10 0
TET1 9 0
DNMT3B 6 0
EZH2 5 0
IDH2 5 0
MBD1 4 1
ZBTB38 0 86
APOBEC3G 0 63
APOBEC3C 2 24
GMDs correlated with ≥ 4 gene regions
SETDB1 54 0
KDM2B 53 0
TET3 41 0
CBX2 39 0
DNMT3A 9 0
DNMT1 7 0
APOBEC3G 0 12
ZBTB38 0 4
APOBEC3C 0 4
  1. Listed are the counts of correlations satisfying p < 1.389 × 10–8 and Spearman |ρ| > 0.5 for individual probes and pFDR < 0.05 and Spearman |ρ| > 0.5 for gene regions