Table 2 GMDs with the highest numbers of strong trans-correlations between their expression and methylation levels of target individual probes and gene regions in pancancer analysis
GMD | Positive correlations | Negative correlations |
|---|---|---|
GMDs correlated with ≥ 5 individual probes | ||
SETDB1 | 422 | 1 |
CBX2 | 383 | 0 |
KDM2B | 352 | 1 |
TET3 | 280 | 0 |
DNMT3A | 43 | 0 |
MGMT | 39 | 0 |
TDG | 20 | 0 |
DNMT1 | 11 | 0 |
EHMT2 | 10 | 0 |
TET1 | 9 | 0 |
DNMT3B | 6 | 0 |
EZH2 | 5 | 0 |
IDH2 | 5 | 0 |
MBD1 | 4 | 1 |
ZBTB38 | 0 | 86 |
APOBEC3G | 0 | 63 |
APOBEC3C | 2 | 24 |
GMDs correlated with ≥ 4 gene regions | ||
SETDB1 | 54 | 0 |
KDM2B | 53 | 0 |
TET3 | 41 | 0 |
CBX2 | 39 | 0 |
DNMT3A | 9 | 0 |
DNMT1 | 7 | 0 |
APOBEC3G | 0 | 12 |
ZBTB38 | 0 | 4 |
APOBEC3C | 0 | 4 |