Fig. 4
From: FK228 sensitizes radioresistant small cell lung cancer cells to radiation
Effects of FK228 and radiation on DDR damage. a, b Western blot analysis of the basal level (a) and the FK228-induced change (b) of histone H3K9Ac in SCLC cell lines. c Time-course analysis of γH2AX and Rad51 in SCLC cells by Western blot. SCLC Cells were cultured with 1 nM FK228 for indicated times. d, e Dose–response analysis of γH2AX and Rad51 in SCLC Cells treated with radiation (4 Gy) (d) or NCS (e), 1 nM FK228, or in combination by Western blot. β-actin was used as a loading control. Relative amount of Rad51 were determined by densitometric analysis