Fig. 3
From: FK228 sensitizes radioresistant small cell lung cancer cells to radiation
The combination effects of FK228 and radiation. a Annexin V apoptotic assay indicates that FK228 enhances radiation-induced apoptosis in radioresistant SCLC cell lines. SCLC cells were treated with DMSO control, 1Â nM FK228, radiation or the combination. After treatment, Annexin V apoptotic assay was performed by flow cytometry. b, c Western blot analysis of cleaved PARP in SCLC cells upon treatment with FK228 or radiation alone and in combination [30] or FK228 or NCS alone and in combination (c)