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Table 2 Univariate and multivariate analysis for progression-free survival (PFS)

From: Hypoxia promotes the metastasis of pancreatic cancer through regulating NOX4/KDM5A-mediated histone methylation modification changes in a HIF1A-independent manner

 

Univariate

Multivariate

 

Hazard ratio

95%CI

p value

Hazard ratio

95%CI

p value

Gender

0.9699

0.6583–1.429

0.8769

   

Hypoxia score

1.861

1.264–2.741

0.0024*

1.646

1.043–2.597

0.032*

Grade

   

–

–

0.139

G1

  

Reference

   

G2

1.623

1.010–2.774

0.0283*

   

G3/G4

2.124

1.199–3.762

0.0089*

   

Stage

   

–

–

0.189

I

  

Reference

   

II

2.745

1.628–4.630

0.0292*

   

III/IV

1.911

0.5360–6.816

0.2483

   

Location (head vs body and tail)

0.5963

0.3738–0.9511

0.057

   

Residual tumor

2.289

1.444–3.628

0.0001*

1.988

1.303–3.035

0.001*

  1. *Statistically significant in the univariate and multivariate analysis