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Fig. 4. | Clinical Epigenetics

Fig. 4.

From: 5-AZA-dC induces epigenetic changes associated with modified glycosylation of secreted glycoproteins and increased EMT and migration in chemo-sensitive cancer cells

Fig. 4.

5-AZA-dC treatment results in increased expression of the cellular senescence marker p21 and increased PARP-cleavage. Protein expression of p16, p21, Rb and PARP normalised to α-tubulin as determined by densitometry (Image J) (Western blots are represented in Additional file 5: Figure S6). Each condition was undertaken on two biological replicates. Significant changes are starred: *p value  ≤ 0.05 or **p value  ≤ 0.005 (T test)

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