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Fig. 3 | Clinical Epigenetics

Fig. 3

From: 5-AZA-dC induces epigenetic changes associated with modified glycosylation of secreted glycoproteins and increased EMT and migration in chemo-sensitive cancer cells

Fig. 3

EMT and cell migration increases in chemo-sensitive cell lines. a Fold change of the protein expression of E-cadherin, vimentin and N-cadherin normalised to α-tubulin as determined by densitometry (Image J) (Western blots are in Additional file 5: Figure S4). Each condition represents three biological replicates. b Quantification of the absorbance readings from the Oris™ migration assay. A comparison of the absorbance from untreated vs 5-AZA-dC treated cells. Error bars were calculated from 3 independent experiments with 4 technical replicates per experiment. Significant changes are starred: *p value ≤ 0.05 or **p value ≤ 0.005 (T test)

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