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Fig. 1. | Clinical Epigenetics

Fig. 1.

From: 5-AZA-dC induces epigenetic changes associated with modified glycosylation of secreted glycoproteins and increased EMT and migration in chemo-sensitive cancer cells

Fig. 1.

5-AZA-dC successfully demethylates global DNA. a Representative example of a flow cytometry dot plot for the PEO1 cell line, both untreated (UnT) and treated with 0.1 µM of 5-AZA-dC, measuring the fluorescent intensity (FI) of both PI and FITC. b Total percentage of DNA methylation post-5-AZA-dC treatment. c Histogram profiles, representing the percentage phases of the cell cycle (G1, S, and G2), before and after 5-AZA-dC treatment. All experiments are n = 3 biological replicates. Error bars represent ± SD. Significant changes are starred: *p value ≤ 0.05 or **p value ≤ 0.005 (T test)

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