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Table 2 Logistic regression analyses of variables for complete remission in AML patients

From: Identification and validation of obesity-related gene LEP methylation as a prognostic indicator in patients with acute myeloid leukemia

Variables

Univariate analysis

Multivariate analysis

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

LEP methylation

0.408 (0.206–0.807)

0.010

0.371 (0.164–0.837)

0.017

Age

0.151 (0.067–0.337)

0.000

0.142 (0.058–0.343)

0.000

WBC

0.284 (0.136–0.593)

0.001

0.545 (0.232–1.280)

0.164

Cytogenetic risks

0.317 (0.178–0.564)

0.000

0.349 (0.190–0.642)

0.001

NPM1 mutations

1.530 (0.481–4.867)

0.472

  

FLT3-ITD mutations

0.819 (0.219–3.071)

0.768

  

C-KIT mutations

2.625 (0.461–14.932)

0.277

  

N/K-RAS mutations

0.381 (0.098–1.487)

0.165

  

DNMT3A mutations

0.480 (0.089–2.581)

0.392

  

U2AF1 mutations

Undermined

0.999

  

IDH1/2 mutations

0.827 (0.133–5.141)

0.838

  

SRSF2 mutations

Undermined

0.999

  

SETBP1 mutations

1.255 (0.077–20.556)

0.874

  
  1. Variables including LEP methylation (hypermethylation vs. non-hypermethylation), age (≤ 60 vs. > 60 years), WBC (≥ 30 × 109 vs. < 30 × 109 /L), and gene mutations (mutant vs. wild-type). Multivariate analysis includes variables with P < 0.100 in univariate analysis