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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Identification and validation of obesity-related gene LEP methylation as a prognostic indicator in patients with acute myeloid leukemia

Fig. 4

MicroRNA signatures correlated with LEP in AML. a Expression heatmap of differentially expressed microRNAs between lower- and higher-expressed LEP in AML patients among TCGA datasets (FDR < 0.05, P < 0.05 and |log2 FC|> 1). b Venn results of microRNAs which could target LEP predicted by TargetScan (http://www.targetscan.org/vert_72/), miRDB (http://mirdb.org/miRDB/), and miRWalk (http://mirwalk.umm.uni-heidelberg.de/). c Venn results of microRNAs shared in the negatively correlated microRNAs in a and the bioinformatics prediction in b

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