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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Identification and validation of obesity-related gene LEP methylation as a prognostic indicator in patients with acute myeloid leukemia

Fig. 1

Identification of prognostically obesity-related genes correlated with DNA methylation in AML. a The impact of obesity-related genes expression on overall survival among AML patients from TCGA databases. AML patients were divided into two groups by the median methylation level of each gene respectively. b Correlation between obesity-related genes expression and methylation among AML patients from TCGA databases. The correlation analysis was conducted by Spearman test. c LEP methylation level in AML patients and controls obtained by bioinformatics analysis. LEP promoter CpG island methylation level was obtained through the human disease methylation database DiseaseMeth version 2.0 (http://bio-bigdata.hrbmu.edu.cn/diseasemeth/analyze.html). TCGA The Cancer Genome Atlas

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