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Table 2 List of the 24 DMPs with an absolute difference in methylation levels > 0.10 between 12 and 24 months of age

From: Changes in epigenetic profiles throughout early childhood and their relationship to the response to pneumococcal vaccination

CpG_ID Chr Position Relation to CGI Gene name Gene group FDR P value Mean value (m12–m24)
cg05825244 chr20 2,730,488 Island EBF4 Body 2.96E−04 − 0.2201
cg25556035 chr19 13,127,873 S_Shelf NFIX Body 4.27E−07 − 0.1930
cg14716990 chr10 129,533,731 N_Shore    9.20E−08 − 0.1523
cg22268510 chr6 32,118,420 Island PRRT1 Body 5.14E−07 − 0.1448
cg10767662 chr19 13,127,729 S_Shelf NFIX Body 3.43E−07 − 0.1407
cg01323777 chr17 7,832,943 Island KCNAB3 TSS200 4.09E−05 − 0.1366
cg00254681 chr6 32,118,457 Island PRRT1 Body 1.01E−06 − 0.1321
cg13138089 chr2 233,251,770 Island ECEL1P2 TSS200 7.75E−03 − 0.1309
cg13870494 chr9 72,658,358 N_Shore MAMDC2 TSS200 2.36E−05 − 0.1244
cg20471691 chr17 46,681,316 N_Shelf LOC404266; LOC404266; HOXB6 Body; body; 5′UTR 4.05E−05 − 0.1164
cg23365801 chr17 7,832,909 Island KCNAB3 TSS200 8.93E−04 − 0.1163
cg23491743 chr2 241,989,271 Island SNED1 Body 2.15E−06 − 0.1141
cg27162435 chr17 7,833,163 Island KCNAB3 TSS1500 8.86E−05 − 0.1099
cg00589520 chr7 23,513,039 N_Shore    1.15E−09 − 0.1053
cg09490371 chr2 233,253,024 Island ECEL1P2 TSS1500 2.54E−03 − 0.1051
cg11617964 chr6 32,118,399 Island PRRT1 Body 1.82E−08 − 0.1027
cg25460807 chr8 21,908,022 S_Shelf    6.25E−04 − 0.1013
cg11041817 chr17 46,685,327 Island HOXB7 Body 4.88E−03 − 0.1011
cg16146033 chr11 62,767,323 OpenSea SLC22A8 Body 5.40E−08 0.1063
cg02481642 chr20 43,343,760 OpenSea WISP2 TSS200 5.78E−06 0.1085
cg25135018 chr1 154,435,948 OpenSea IL6R; IL6R Body; body 1.16E−06 0.1099
cg06688910 chr8 122,466,955 OpenSea    6.72E−08 0.1101
cg17945323 chr11 62,767,406 OpenSea SLC22A8 Body 6.66E−09 0.1103
cg09978533 chr22 46,465,160 N_Shore    9.39E−06 0.1149
  1. The top 18 CpGs are hypermethylated, while the bottom 6 CpGs are hypomethylated in samples from 24 months compared with 12 months of age
  2. Chr chromosome, *N_Shore/N_Shel North Shore/Shelf, S_Shore/S_Shelf South Shore/Shelf
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