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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Changes in epigenetic profiles throughout early childhood and their relationship to the response to pneumococcal vaccination

Fig. 6

a Principal components analysis and b unsupervised clustering with heatmap of 4067 differentially methylated CpG sites (uncorrected P value < 0.01) at 12 months of age and grouping by high and low vaccine responders. c Boxplots showing 4 DMPs associated with hypomethylation of HLA-DPB1 and 2 DMPs associated with hypermethylation of IL6 in high vaccine responders. The y-axis represents the β value for each position in both groups (yellow for high responders, light blue for low responders)

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