Table 1 Univariate and multivariate cox regression analysis of acute myeloid leukemia patients (n = 241)

Cytogenetic category

chr –5, –7

0.69

0.21–2.30

0.54

chr –5, –7, + 8

0.54

0.12–2.44

0.43

chr –7

0.63

0.21–1.93

0.42

11q23

0.32

0.10–1.08

0.07

chr + 21

0.09

0.02–0.51

0.01

0.09

0.02–0.51

0.01

chr 5q–

0.94

0.10–8.43

0.95

chr 7q–

2.92

0.32–26.83

0.34

chr + 8

0.36

0.12–1.12

0.08

Diploid

0.24

0.09–0.66

0.01

0.23

0.08–0.64

 < 0.01

Inv(9)

0.64

0.12–3.53

0.61

ssInv(16)

0.05

0.01–0.20

0.00

0.05

0.01–0.18

 < 0.01

Miscellaneous

0.30

0.11–0.85

0.02

0.30

0.11–0.84

0.02

t(6;9)

0.32

0.08–1.29

0.11

t(8;21)

0.06

0.01–0.27

0.00

0.06

0.01–0.27

 < 0.01

FLT3

ITD

1.22

0.86–1.73

0.26

D835

0.75

0.43–1.29

0.30

Any

1.21

0.86–1.69

0.28

NPM1

1.07

0.71–1.61

0.74

DNMT3A

0.94

0.46–1.93

0.87

IDH

IDH1

0.76

0.43–1.35

0.35

IDH2

1.50

0.88–2.56

0.13

Any

1.03

0.67–1.58

0.91

P53

2.50

1.14–5.55

0.02

RAS

0.68

0.45–1.04

0.07

PTPN11

0.53

0.21–1.32

0.17

TET2

1.62

0.89–2.87

0.11

H3K27Me3

Continuous

0.74

0.58–0.94

0.01

0.74

0.57–0.95

0.02