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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Loss of H3K27 methylation identifies poor outcomes in adult-onset acute leukemia

Fig. 1

a Heatmap showing histone methylation levels in bone marrow (BM) derived samples from AML (n = 162) and ALL (n = 79) patients. b Lower H3K27me3 protein expression in BM derived AML samples compared to normal BM (NBM, n = 10) and BM derived ALL samples. c Heatmap showing histone methylation levels in peripheral blood (PB) samples from AML (n = 79) and ALL (n = 48) patients. d Lower H3K27me3 protein expression in PB derived AML samples compared to NBM and PB derived ALL samples. ****p < 0.0001, ns = not significant. e Heatmap combining AML and ALL samples from both sources along with cytogenetic information, presence of FLT3 or NPM1 mutation and age group

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