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Table 1 Basic characteristics and plasma copper concentrations of the study participants

From: Profile of copper-associated DNA methylation and its association with incident acute coronary syndrome

Characteristicsa DFTJ (n = 682) ACS-WH (n = 90) ACS-GD (n = 98) WHZH (n = 230) SY
(n = 143)
Age, years 65.2 ± 6.3 59.3 ± 10.0 59.3 ± 11.4 54.5 ± 13.2 41.4 ± 10.2
Male, n (%) 355 (52.1) 74 (82.2) 78 (79.6) 182 (79.1) 106 (74.1)
Smoking status, n (%)  
 Current smoker 160 (23.5) 33 (36.7) 41 (41.8) 95 (41.3) 45 (31.5)
 Former smoker 85 (12.5) 23 (25.6) 13 (13.3) 23 (10.0) 2 (1.4)
 Never smoker 437 (64.1) 34 (37.8) 44 (44.9) 112 (48.7) 96 (67.1)
Drinking status, n (%)  
 Current drinker 164 (24.0) 21 (23.3) 20 (20.4) 65 (28.3) 54 (37.8)
 Former drinker 30 (4.4) 0 (0.0) 0 (0.0) 5 (2.2) 1 (0.7)
 Never drinker 488 (71.6) 69 (76.7) 78 (79.6) 160 (69.6) 88 (61.5)
BMI, kg/m2 24.9 ± 3.2 24.8 ± 2.8 23.0 ± 2.4 23.2 ± 2.6 24.2 ± 2.7
Systolic blood pressure, mmHg 128.9 ± 17.1 129.9 ± 20.5 134.5 ± 25.3 129.1 ± 16.7 130.7 ± 18.1
Diastolic blood pressure, mmHg 75.4 ± 10.3 81.2 ± 13.4 79.1 ± 13.8 76.9 ± 9.8 80.2 ± 12.1
Fasting glucose, mmol/L 6.1 ± 1.6 5.3 ± 0.8 6.9 ± 1.7 4.7 ± 1.3 5.5 ± 0.7
Triglyceride, mmol/L 1.5 ± 1.0 1.7 ± 1.1 1.5 ± 1.0 1.4 ± 1.0 1.4 ± 1.0
Total cholesterol, mmol/L 5.3 ± 0.9 3.9 ± 1.0 4.9 ± 1.2 5.1 ± 1.1 4.9 ± 0.8
HDL-C, mmol/L 1.4 ± 0.3 1.1 ± 0.3 1.2 ± 0.2 1.5 ± 0.4 1.4 ± 0.3
LDL-C, mmol/L 3.1 ± 0.8 2.1 ± 0.8 3.1 ± 0.9 3.0 ± 1.0 2.9 ± 0.7
Major leukocyte compositions  
 Basophil proportion, % 1.3 ± 0.4 1.3 ± 1.2
 Eosinophil proportion, % 2.2 ± 1.6 2.1 ± 1.6
 Monocyte proportion, % 7.3 ± 1.7 4.9 ± 2.7
 Lymphocyte proportion, % 32.8 ± 8.6 28.3 ± 9.9 19.5 ± 11.9 38.0 ± 8.2 33.6 ± 7.5
 Neutrophil proportion, % 57.0 ± 9.0 62.6 ± 10.4 72.3 ± 13.4 55.3 ± 8.4 58.0 ± 8.2
 Intermediate cells proportionb, % 10.7 ± 10.7 9.1 ± 3.1 8.2 ± 4.0 6.8 ± 3.7 8.3 ± 2.7
 C-reactive protein, mg/L 2.5 ± 4.3 1.6 ± 3.7 0.8 ± 1.3
 Plasma copper (μg/L) 951.5 ± 178.6 812.0 ± 183.5 897.7 ± 495.5 899.7 ± 194.3 782.5 ± 141.7
  1. DFTJ the Dongfeng-Tongji Cohort, ACS-WH ACS patients recruited in Wuhan, ACS-GD ACS patients recruited in Zhuhai, WHZH participants from the Wuhan-Zhuhai cohort, SY healthy individuals from Shiyan, China
  2. aThe continuous variables are presented as mean ± SD. Categorical variables are presented as n (%)
  3. bIntermediate cells consist of monocytes, eosinophils, and basophils
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