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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Epigenetic modifications in muscle regeneration and progression of Duchenne muscular dystrophy

Fig. 6

Cell signaling pathways in the epigenetic regulation of myogenesis. p38α/β MAPK, p38γ MAPK, IGF1/Pi3K/AKT, CaMK, Wnt/β-catenin, and nNOS signaling either inactivates (marked red) or activates (marked green) downstream targets, dependent on the stage of the muscle formation. The consequences following particular signaling events and the final impact on myogenesis (in italics) are listed below the name of each signaling pathway

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