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Table 4 Significant enrichment of GO terms in the top 500 sites from the Discovery Cohort EWAS of PTSD

From: An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci

TermOntNDEppadjGenes
GO:0032496: response to lipopolysaccharideBP322196.97E − 060.042PPARGC1A, CNR2, CPS1, TICAM1, ELANE, FGFR2, FOXP1, TICAM2, IL1B, MEF2C, ABCB4, PRKCE, ERBIN, HAMP, RARA, TFPI, VDR, CDC73, TNIP3
GO:0030374: ligand-dependent nuclear receptor transcription coactivator activityMF6991.12E − 050.042PPARGC1A, NCOA7, PPARG, PRKCB, RARA, RARB, RORA, VDR, MED12
GO:0002237:response to molecule of bacterial originBP339191.42E − 050.042PPARGC1A, CNR2, CPS1, TICAM1, ELANE, FGFR2, FOXP1, TICAM2, IL1B, MEF2C, ABCB4, PRKCE, ERBIN, HAMP, RARA, TFPI, VDR, CDC73, TNIP3
GO:0071216: cellular response to biotic stimulusBP202141.71E − 050.042PPARGC1A, TICAM1, TICAM2, IL1B, MEF2C, ABCB4, PRKCE, HAMP, RARA, TFPI, VDR, WFS1, CDC73, TNIP3
GO:0003416: endochondral bone growthBP2261.75E − 050.042FGFR2, POC1A, MSX2, BNC2, RARA, RARB
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