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Fig. 6 | Clinical Epigenetics

Fig. 6

From: H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade

Fig. 6

H3K27me3 expression in the invasion front and the inner tumor mass of cutaneous melanoma metastases. Two representative cutaneous melanoma metastases in 2.5-fold, 5-fold, and 40-fold magnification (from left to right) with presentation of invasion front (a) and inner tumor mass (b). No H3K27me3 positive cells can be observed in the inner tumor mass, while the invasion front of both cutaneous metastases shows 60% H3K27me3 positive melanoma cells

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