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Fig. 3 | Clinical Epigenetics

Fig. 3

From: H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade

Fig. 3

Immunohistochemical classification of H3K27me3 expression. Establishment of immunhistochemical staining for H3K27me3 in primary melanomas. a Without H3K27me3 expression (0% positive cells) in 2.5-fold, 10-fold, and 40-fold magnification. b With 5% H3K27me3 positive melanoma cells in 2.5-fold, 10-fold, and 40-fold magnification. c With 50% H3K27me3 positive melanoma cells in 2.5-fold, 10-fold, and 40-fold magnification. d With 70% H3K27me3 positive melanoma cells in 2.5-fold, 10-fold, and 40-fold magnification

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