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Fig. 2 | Clinical Epigenetics

Fig. 2

From: H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade

Fig. 2

H3K27me3 and EZH2 expression of melanoma metastases prior to anti-PD-1 therapy. a H3K27me3 and EZH2 expression of melanoma metastases (in %) in correlation to response to anti-PD-1 inhibition. Significance was determined by Χ2 test for categorical data. b Percentage of H3K27me3-positive melanoma cells in correlation to percentage of EZH2-positive melanoma cells. Significance was determined by Spearman’s rank correlation test (p = .002)

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