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Fig. 1. | Clinical Epigenetics

Fig. 1.

From: Accumulation of DNA methylation alterations in paediatric glioma stem cells following fractionated dose irradiation

Fig. 1.

Schematic representation of the model system and experimental setup of fractionated dose irradiation schemes. a Paediatric high-grade glioma stem cell cultures established pre- or post-radiotherapy (30 fractions irradiation of 1.8 Gy each) were used in the study. b Cells were exposed to 3–18 fractionated dose irradiations 2–8 Gy. To monitor the stability during culturing, GU-pBT-07 cells were cultured and analysed at passage 12 and 22. These sub-cultured cells from early (p12) and later passages (p22) were irradiated and used as biological replicates

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